Assessing rTMS effects in MdDS: Cross-modal comparison between resting state EEG and fMRI connectivity MdDS Foundation 12:01 am 7.11.2017 Assessing rTMS effects in MdDS: Cross-modal comparison between resting state EEG and fMRI connectivity Abstract Repetitive transcranial magnetic stimulation (rTMS) has been increasingly explored for many neurological and neuropsychiatric conditions. However, the response rate is variable depending on baseline conditions. Optimizing rTMS protocols to improve treatment effects and response rates will depend on reliably assessing brain state conditions. In this regard, neural activity guided optimization has shown potential in […] Read More
Double-blind sham-controlled crossover trial of repetitive transcranial magnetic stimulation for mal de debarquement syndrome MdDS Foundation 12:01 am 5.12.2016 Double-blind sham-controlled crossover trial of repetitive transcranial magnetic stimulation for mal de debarquement syndrome Abstract Objective: To determine whether the chronic rocking dizziness that occurs in Mal de Debarquement Syndrome (MdDS) can be suppressed with repetitive transcranial magnetic stimulation (rTMS) beyond the treatment period. Methods: We performed a prospective randomized double-blind sham controlled crossover trial of 5-days of rTMS utilizing high frequency (10 Hz) stimulation over the left dorsolateral […] Read More
Randomized single blind sham controlled trial of adjunctive home-based tDCS after rTMS for mal de debarquement syndrome: safety, efficacy, and participant satisfaction assessment MdDS Foundation 12:01 am 3.30.2016 Randomized single blind sham controlled trial of adjunctive home-based tDCS after rTMS for mal de debarquement syndrome: safety, efficacy, and participant satisfaction assessment Brain Stimulation, July–August, 2016, Volume 9, Issue 4, Pages 537–544 Abstract Background: Mal de debarquement syndrome is a medically refractory disorder characterized by chronic rocking dizziness that occurs after exposure to passive motion. Repetitive transcranial magnetic stimulation (rTMS) can acutely suppress the rocking dizziness but treatment options that extend the benefit of rTMS are needed. Objectives: 1) […] Read More
Voxel based morphometry alterations in mal de debarquement syndrome MdDS Foundation 12:01 am 8.7.2015 Voxel based morphometry alterations in mal de debarquement syndrome AbstractBackground: Mal de debarquement syndrome (MdDS) is a disorder of chronic self-motion perception that occurs though entrainment to rhythmic background motion, such as from sea voyage, and involves the perception of low-frequency rocking that can last for months or years. The neural basis of this persistent sensory perception abnormality is not well understood.Methods: We investigated […] Read More
Mal de Debarquement Syndrome: new insights MdDS Foundation 12:01 am 2.27.2015 Mal de Debarquement Syndrome: new insights Dizziness and Balance Disorders, Vol. 1343:1, Pages 63-68, April 2015ABSTRACTMal de Debarquement Syndrome (MdDS) is an enigmatic neurotological disorder with high morbidity, psychosocial burden, and few treatment options. Fortunately, there has been recent growth in scientific interest in understanding the biological basis of and in treating MdDS. Recent studies using functional neuroimaging have shown increased glucose metabolism in the […] Read More
The relationship between symptom severity, stigma, illness intrusiveness and depression in Mal de Debarquement Syndrome MdDS Foundation 12:01 am 10.20.2014 The relationship between symptom severity, stigma, illness intrusiveness and depression in Mal de Debarquement Syndrome Abstract Mal de Debarquement Syndrome is a neurological disorder of motion perception, triggered by external motion. This study aimed to determine the importance of psychosocial factors in relation to depression and quality of life in Mal de Debarquement Syndrome. A total of 66 participants with self-reported Mal de Debarquement Syndrome completed quality-of-life, symptom severity, stigma, […] Read More
Changes of symptom and EEG in mal de debarquement syndrome patients after repetitive transcranial magnetic stimulation over bilateral prefrontal cortex: A pilot study MdDS Foundation 12:01 am 10.1.2014 Changes of symptom and EEG in mal de debarquement syndrome patients after repetitive transcranial magnetic stimulation over bilateral prefrontal cortex: A pilot study Abstract Mal de debarquement syndrome (MdDS) is a chronic disorder of imbalance characterized by a feeling of rocking and swaying. The medical treatment for MdDS is still limited. Motivated by our previous pilot study that demonstrates the promising clinical efficacy of repetitive transcranial stimulation (rTMS) in MdDS patients, a novel rTMS paradigm, i.e., 1 Hz […] Read More
Lasting Modulation Effects of rTMS on Neural Activity and Connectivity as Revealed by Resting State EEG MdDS Foundation 12:01 am 7.1.2014 Lasting Modulation Effects of rTMS on Neural Activity and Connectivity as Revealed by Resting State EEG Abstract The long-lasting neuromodulatory effects of repetitive transcranial magnetic stimulation (rTMS) are of great interest for therapeutic applications in various neurological and psychiatric disorders, due to which functional connectivity among brain regions is profoundly disturbed. Classic TMS studies selectively alter neural activity in specific brain regions and observe neural activity changes on nonperturbed areas to […] Read More
