Persistent Oscillating Vertigo From Extracranial Venous Compression MdDS Foundation 1:46 pm 9.18.2025 Persistent Oscillating Vertigo From Extracranial Venous Compression Persistent oscillating vertigo (POV) can be triggered by motion, when it is called mal de débarquement syndrome (MdDS) but can also occur from nonmotion triggers such as neck injury, inflammation, or homeostatic derangements (nonmotion POV [nmPOV]). The pathology underlying MdDS and nmPOV is unknown but shared symptoms include rocking/bobbing/swaying vertigo, headache, cognitive slowing, and fatigue. Read More
Update on therapies for Mal de Débarquement Syndrome MdDS Foundation 12:01 am 8.19.2022 Update on therapies for Mal de Débarquement Syndrome Abstract Purpose of Review This review will discuss current treatment options for mal de débarquement syndrome (MdDS) and non-motion triggered persistent oscillating vertigo (nmPOV). Therapies available in most clinical settings such as modifying homeostatic factors (sleep, stress, menstrual cycle, visual stimulation), medications (benzodiazepines, serotonin reuptake inhibitors), and vestibular/physical therapy are discussed. Travel precautions should incorporate […] Read More
Psychological assessment of individuals with Mal de Débarquement Syndrome MdDS Foundation 12:01 am 4.1.2022 Psychological assessment of individuals with Mal de Débarquement Syndrome Abstract Objective: To report on the psychological, personality, and behavioral profiles of individuals with persistent Mal de Débarquement Syndrome (MdDS). Materials and methods: Individuals with MdDS who participated in neuromodulation clinical trials between May 2013 and June 2019 completed a series of standardized psychological questionnaires and underwent the Structural Clinical Interview for DSM-IV-TR (SCID) for […] Read More
Double-blind randomized N-of-1 trial of transcranial alternating current stimulation for mal de débarquement syndrome MdDS Foundation 12:01 am 2.4.2022 Double-blind randomized N-of-1 trial of transcranial alternating current stimulation for mal de débarquement syndrome Abstract Background: Mal de Débarquement Syndrome (MdDS) is a medically refractory neurotological disorder characterized by persistent oscillating vertigo that follows a period of entrainment to oscillating motion such as experienced during sea or air travel. Fronto-occipital hypersynchrony may correlate with MdDS symptom severity. Materials and methods: Individuals with treatment refractory MdDS lasting at least 6 […] Read More
Remotely Monitored Home-Based Neuromodulation With Transcranial Alternating Current Stimulation (tACS) for Mal de Débarquement Syndrome MdDS Foundation 12:01 am 12.9.2021 Remotely Monitored Home-Based Neuromodulation With Transcranial Alternating Current Stimulation (tACS) for Mal de Débarquement Syndrome Abstract Objective: To determine whether remotely-monitored transcranial alternating current stimulation (tACS) may be a viable and safe treatment option for Mal de Débarquement Syndrome (MdDS). Background: Mal de Débarquement Syndrome is a neurotological disorder characterized by persistent oscillating vertigo that is triggered by entrainment to passive oscillatory motion such as occurs during water-based travel. Treatment […] Read More
Brain network effects by continuous theta burst stimulation in mal de débarquement syndrome: simultaneous EEG and fMRI study MdDS Foundation 12:01 am 11.30.2021 Brain network effects by continuous theta burst stimulation in mal de débarquement syndrome: simultaneous EEG and fMRI study Abstract Objective. Heterogeneous clinical responses to treatment with non-invasive brain stimulation are commonly observed, making it necessary to determine personally optimized stimulation parameters. We investigated neuroimaging markers of effective brain targets of treatment with continuous theta burst stimulation (cTBS) in mal de débarquement syndrome (MdDS), a balance disorder of persistent oscillating vertigo previously shown to […] Read More
fMRI and transcranial electrical stimulation (tES): A systematic review of parameter space and outcomes MdDS Foundation 12:01 am 4.20.2021 fMRI and transcranial electrical stimulation (tES): A systematic review of parameter space and outcomes Abstract The combination of non-invasive brain stimulation interventions with human brain mapping methods have supported research beyond correlational associations between brain activity and behavior. Functional MRI (fMRI) partnered with transcranial electrical stimulation (tES) methods, i.e., transcranial direct current (tDCS), transcranial alternating current (tACS), and transcranial random noise (tRNS) stimulation, explore the neuromodulatory effects of tES […] Read More
Remotely monitored home-based transcranial alternating current stimulation for mal de debarquement syndrome MdDS Foundation 12:01 am 4.13.2021 Remotely monitored home-based transcranial alternating current stimulation for mal de debarquement syndrome Abstract Objective: To determine whether remotely monitored at-home Transcranial Alternating Current Stimulation (tACS) may be an effective and safe treatment option for Mal de Débarquement Syndrome (MdDS). Background: Treatment options for MdDS are limited, costly, and difficult to access. This study explored the viability of an at-home, self-administered tACS program for treatment of MdDS. The […] Read More
