How is MdDS different from motion sickness? The Key Distinction: Motion sickness is a transient physiological response to motion that resolves quickly. In contrast, Mal de Débarquement Syndrome is a neurological disorder where symptoms persist for at least 30 days.While both conditions involve spatial disorientation, MdDS and motion sickness are distinct in their attributes and suspected mechanisms. Understanding the distinction between motion sickness and MdDS can help guide your management path. Motion Sickness MdDS (Mal de Débarquement Syndrome) Occurs during passive motion (e.g., riding in a car, boat, or plane). Typically occurs after passive motion ceases (e.g., stepping back onto solid land).* A transient sensory conflict where visual and peripheral vestibular (inner ear) inputs disagree. Research suggests a central vestibular (neurological) basis involving altered brain network connectivity and vestibular processing, though the exact cause needs more research. Symptoms generally stop once the passive motion ceases. Symptoms temporarily improve when the individual is back in passive motion (e.g., driving a car). Short-term; usually resolves within hours after the motion stops. Two weeks is within normal range. Prolonged or chronic; symptoms persist for months, years, or indefinitely.